Mammary Gland Changes During Chlorpromazine Therapy

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P-188: Mammary Gland Changes during Chlorpromazine Treatment in Female Rats

Background: Antipsychotic drugs are medications used to treat schizophrenia and other psychotic disorders. Antipsychotic drugs can cause unwanted side effects. Hyperprolactinemia is an important but neglected adverse effect. The aim of the this study was to consider the effects of Chlropromazine -induced hyperprolactinaemia on mammary glands of female rats . Materials and Methods: In this study...

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Optic atrophy during chlorpromazine therapy.

Chlorpromazine hydrochloride, a synthetic phenothiazine, has been widely employed in psychiatric illnesses, and an extensive literature exists on its side-effects; many reports describe ocular changes, including an oculo-dermal melanosis with deposition of pigment in the retina (Feldman and Frierson, I964; Zelickson and Zeller, I964; Cairns, Capoore, and Gregory, I965; Brit. med. J., I967), dep...

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Corneal changes in long-term chlorpromazine therapy

Objective: To study ocular manifestations in patients who were on long-term use of chlorpromazine. Methods: A retrospective observational case study was made. Three patients, who were diagnosed as Schizophrenia and on long-term use of chlorpromazine for more than 20 years, were examined retrospectively. The examinations included clinical history, physical examination, slit-lamp biomicroscopy, a...

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ژورنال

عنوان ژورنال: BMJ

سال: 1957

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5048.806